Can Withdrawal Kill You
Withdrawal from addictive substances is a serious medical condition. It is more than discomfort or cravings. Can withdrawal kill you though? In some cases, the withdrawal process can lead to severe health issues—and yes, it can be fatal. Knowing the dangers and seeking help through medical supervision can reduce the risk of death and support long-term recovery.
People often underestimate the risks of drug withdrawal and assume they can quit cold turkey without help. However, withdrawal is not simply about willpower. It’s a physical and psychological response that can place extreme stress on the body. Without proper medical care, certain substances—especially alcohol and benzodiazepines—can trigger dangerous symptoms, including seizures, heart palpitations, and even heart failure. These risks are especially high for individuals with substance use disorders or those struggling with co-occurring disorders. Understanding the severity of withdrawal is the first step toward making informed, safe decisions about treatment. Here’s what you need to know.
What Is Withdrawal?
Withdrawal is the body’s reaction to stopping or reducing the use of a substance it has become dependent on. People with physical dependence may develop withdrawal symptoms within hours of stopping the substance. The severity of symptoms depends on the substance, duration of use, and individual health.
The types of withdrawal include alcohol, opioids, benzodiazepines, stimulants, and others. Each has its own risks and complications. Some are uncomfortable but not life-threatening. Others—like Alcohol withdrawal syndrome or benzodiazepine withdrawal syndrome—can be fatal without medical care.
Symptoms of Withdrawal
Withdrawal causes both physical symptoms and psychological symptoms. These symptoms depend on the substance used, how long it was used, and the individual’s health. While some symptoms are uncomfortable but manageable, others can be life-threatening.
Common symptoms of withdrawal include:
- Muscle aches
- Muscle spasms
- Nausea and vomiting
- Diarrhea
- Headaches
- Insomnia or disrupted sleep patterns
- Excessive sweating and chills
- Heart palpitations
- Irregular or increased heart rate
- Elevated blood pressure
- Shaking or tremors
- Sensitivity to light and sound
- Irritability, anxiety, and depression
- Disorientation, confusion, or hallucinations
- Seizures
These symptoms can appear quickly—often within hours of stopping use—and may intensify rapidly. Some individuals experience mild symptoms such as restlessness and fatigue, while others develop severe forms of withdrawal that include violent tremors, hallucinations, and loss of consciousness. Severe symptoms, especially those involving the cardiovascular or nervous system, can result in life-threatening complications. For example, high blood pressure, rapid heart rate, and heart palpitations can place extreme stress on the body. In high-risk cases, this can lead to a heart attack, heart failure, or seizures.
It’s important to remember that each person’s withdrawal experience is different. Even those who have gone through withdrawal before may encounter new or dangerous symptoms during future detox attempts. This is why professional support and medical supervision are essential during the withdrawal process
Alcohol Withdrawal: The Most Dangerous
Alcohol withdrawal syndrome is widely recognized as one of the most dangerous types of withdrawal. This is because alcohol affects several critical systems in the body, especially the central nervous system. When a person with alcohol use disorder suddenly stops drinking, the body is forced to adjust rapidly—often with serious consequences. Chronic alcohol use suppresses brain activity over time. When alcohol is removed, the brain rebounds with excessive excitability. This sudden shift can trigger a flood of withdrawal symptoms, many of which affect the cardiovascular and neurological systems.
Symptoms of alcohol withdrawal usually begin within 6 to 24 hours after the last drink and can include:
- Tremors
- Sweating
- Nausea
- Insomnia
- Heart palpitations
- High blood pressure
- Anxiety
These symptoms can quickly worsen, especially in people with a history of long-term or heavy drinking. In severe forms, symptoms may progress to a life-threatening condition called Delirium Tremens (DTs). Delirium Tremens is the most serious form of alcohol withdrawal and typically develops 48 to 72 hours after alcohol cessation. It includes:
- Severe confusion and disorientation
- Visual and auditory hallucinations
- Intense agitation
- Uncontrollable shaking
- Seizures
- Extremely high blood pressure and heart rate
These effects place immense strain on the heart, brain, and other vital organs. DTs can lead to heart attack, stroke, respiratory failure, or death from alcohol withdrawal if not treated urgently. According to StatPearls Publishing, the mortality rate for untreated DTs is up to 37%. However, with medical detox programs and constant medical supervision, that number drops significantly. Early recognition of dangerous withdrawal symptoms, along with access to medications and vital sign monitoring, makes a critical difference in outcomes.
What makes alcohol withdrawal syndrome especially dangerous is how quickly symptoms can escalate. A person may appear stable at first, only to experience seizures or cardiac issues hours later. This unpredictability makes it vital that people detoxing from alcohol do so in a controlled setting, under the care of healthcare professionals who can intervene immediately. Alcohol withdrawal is not just uncomfortable—it can be fatal. That’s why treatment in a licensed facility with an experienced medical team is essential for safety and survival.

Opiate Withdrawal: Intense and Risky
Opiate withdrawal is typically not fatal on its own. However, the symptoms can be so distressing that they increase the risk of relapse, overdose, and complications. Common opioid withdrawal symptoms include:
- Severe muscle aches
- Restlessness
- Vomiting and diarrhea
- Intense cravings
- Runny nose and yawning
- Fever and chills
Some individuals with opioid dependence experience dangerous withdrawal symptoms such as dehydration, rapid heart rate, and physical injuries from uncontrollable movement or vomiting. In rare cases, the stress of withdrawal on the body, especially in people with other co-occurring disorders or chronic conditions, can contribute to complications such as heart failure or stroke.
Benzodiazepine Withdrawal: A Medical Emergency
Benzodiazepine withdrawal syndrome is another potentially fatal condition. Stopping drugs like Xanax, Ativan, or Valium suddenly can cause:
- Panic attacks
- Insomnia
- Hallucinations
- Seizures
- Psychosis
Seizures are the greatest risk and can lead to heart attack or risk of death. Like alcohol, benzodiazepine withdrawal requires medical supervision to reduce the danger.
Can Withdrawal Kill You?
Yes, severe withdrawal can kill. Withdrawal-related deaths are typically linked to alcohol, benzodiazepines, and co-ingestion of multiple substances. Dangerous withdrawal symptoms include:
- Seizures
- Hallucinations
- High blood pressure
- Irregular heart rate
- Heart palpitations
- Confusion
- Delirium
- Loss of consciousness
If untreated, these symptoms can result in heart failure, stroke, or death from alcohol withdrawal.
The Role of Medical Detox
Medical detox is the safest way to manage withdrawal. Detox allows for 24/7 monitoring by healthcare professionals. In a rehab facility, a medical team monitors vital signs like blood pressure and heart rate, provides fluids, and administers medication.
Medication-assisted treatment can reduce cravings, control symptoms, and prevent complications. Medications used during detox include:
- Benzodiazepines (for treatment of alcohol withdrawal)
- Anticonvulsants
- Beta-blockers (to manage heart rate and blood pressure)
- Buprenorphine (for opioid withdrawal syndrome)
These help patients complete the detox process safely, improving outcomes and reducing the mortality rate.

Who Needs Medical Supervision During Withdrawal?
Withdrawal should always be taken seriously. Anyone with the following risk factors should seek medical supervision:
- History of alcohol abuse or drug addiction
- Previous seizures or Alcohol withdrawal seizures
- Diagnosed Mental Disorders or co-occurring disorders
- Long-term use of addictive substances
- Use of multiple substances
- Underlying heart or liver conditions
Even people with mild symptoms at first can develop severe withdrawal symptoms quickly.
Complications of Alcohol Withdrawal and Other Substances
The complications of alcohol withdrawal are some of the most studied. However, Drug withdrawal syndromes for opioids, stimulants, and other substances can also be dangerous. Risks include:
- Falls or injuries from confusion or tremors
- Choking from vomiting
- Dehydration
- Heart attack or stroke
- Risk of relapse, especially when symptoms are untreated
Avoiding medical care during withdrawal increases these risks. That’s why entering a licensed addiction treatment center or treatment centers with medical detox programs is critical.
Psychological and Physical Recovery
The withdrawal process is the first step of the recovery journey. Once the body is stabilized, people can begin addressing the emotional and mental aspects of substance use disorders.
After detox, patients may enter a rehab facility offering ongoing therapy, including:
- Cognitive-behavioral therapy (CBT)
- Group counseling
- Holistic therapies like yoga and meditation
- 12-step meetings
At Preferred Restoration Services, our addiction treatment center in Orange County offers both intensive outpatient and partial hospitalization levels of care. We specialize in treating addiction and co-occurring disorders with a combination of clinical care, 12-step principles, and holistic support.

The Importance of Professional Help
Choosing to quit drugs or alcohol is a major decision. Trying to detox alone can lead to dangerous symptoms, complications, or death. Working with a medical professional ensures your safety and increases your chance of long-term success.
People often underestimate how quickly withdrawal can become life-threatening. Many deaths occur when people assume their symptoms will stay mild or don’t understand the severe forms that can develop.
Conclusion
Withdrawal can be deadly—but it doesn’t have to be. With proper medical care, professional help, and a safe environment, people can survive even the most severe forms of withdrawal. If you or a loved one is considering quitting alcohol or drugs, don’t do it alone.
Reach out to a licensed rehab facility like Preferred Restoration Services in Orange County. Our expert medical team is here to help you through the withdrawal process and into lasting recovery.

FAQ
Yes, it’s possible, though less common. The risk of death is higher with long-term use, but some individuals may still experience dangerous withdrawal symptoms after short-term or binge use—especially with alcohol, benzodiazepines, or a mix of substances. Even if use was short-lived, factors like underlying mental disorders, heart conditions, or physical dependence can increase the risk. Always consult a medical professional before attempting to quit.
No, withdrawing at home without medical supervision can be dangerous and even fatal, depending on the substance and your health. Over-the-counter remedies might relieve mild discomfort, but they cannot address serious risks like seizures, irregular heart rate, or high blood pressure. Medical detox in a supervised setting is the safest option.
Yes. Older adults, people with chronic medical conditions, individuals with a history of seizures, and those with co-occurring disorders face a much higher risk of death during withdrawal. Additionally, those withdrawing from multiple substances at once—such as alcohol and opioids—are at greater risk of developing severe withdrawal symptoms.
Not always. Some people experience mild symptoms at first that quickly evolve into severe forms of withdrawal without warning. While factors like substance type, length of use, and medical history can help predict risk, symptoms can escalate unpredictably. This is why early assessment by a medical professional and access to medical care are crucial.
Sources
- National Institute on Drug Abuse (NIDA)
- Topic: Withdrawal symptoms, opioid withdrawal, and treatment
- URL: https://nida.nih.gov
2. Substance Abuse and Mental Health Services Administration (SAMHSA)
- Topic: Medication-assisted treatment, substance use disorders, and detox
- URL: https://www.samhsa.gov
3. MedlinePlus (U.S. National Library of Medicine)
- Topic: Alcohol withdrawal, withdrawal symptoms, and health risks
- URL: https://medlineplus.gov/ency/article/000764.htm
4. Centers for Disease Control and Prevention (CDC)
- Topic: Drug overdose deaths, complications of withdrawal
- URL: https://www.cdc.gov/drugoverdose/index.html
5. American Psychiatric Association (APA.org)
- Topic: Alcohol use disorder and diagnostic criteria
- URL: https://www.psychiatry.org
6. National Institutes of Health (NIH)
- Topic: Physical dependence, withdrawal mechanisms
- URL: https://www.nih.gov